Faculty Students Alumni Trainees
Funded Projects Student Projects
Drug Discovery Augmentation Biomarker
Genomics Fox MCGT AIM BLAST Bioinfotracker
Cangene Base RECDB ECOMP BCDB TAXKB
Bioinformatics CTM
 
 
 
 

Publications

Peer Reviewed Journals

 2014

43.TK Subazini and G.Ramesh Kumar (2014) ASPMP – A Biochemical Pathway Resource for Aspergillus terreus NIH2624.Onl J Bioinform.15 (1): 133-140.                                                                               

42.Rajadurai Chinnasamy Perumal, Ashok Selvaraj and Gopal Ramesh Kumar (2014) Elementary Flux Mode Analysis of Acetyl-CoA Pathway in Carboxydothermus hydrogenoformans Z-2901. Adv in Bioinformatics. (Accepted)

41.R. Vijayaraghavan ,Jayanthi Swamnathan,Ashok Selvaraj  and Gopal Ramesh Kumar (2014) GLP (Good Laboratory Practice) guidelines in academic and clinical research: Ensuring Protection and safety.JOURNAL OF PHARMACEUTICAL RESEARCH AND CLINICAL PRACTICE  (JPRCP) (Accepted)

40.Ashok Selvaraj, Subazini Thankaswamy Kosalai, Rajadurai Chinnasamy Perumal, Subhashini Pitchai and Gopal Ramesh Kumar (2013) A Whole Genome pairwise Comparative and Functional analysis of Geobacter sulfurreducens PCA. ISRN Computational Biology. vol. 2013, Article ID 850179, 6 pages, 2013. doi:10.1155/2013/850179.

39.Gopal Ramesh Kumar, Thankaswamy Kosalai Subazini and Ashok Selvaraj (2014) ECO-MP: E coli –Metabolic Pathway-Development of Genome-Scale Metabolic Pathway Database for Escherichia coli. Trends in Bioinformatics(Accepted).                 

2013

38.C.P.Rajadurai, Ashok S, Nupoor Chowdhary and G. Ramesh Kumar (2013) Functional and comparative analysis of novel dehydrogenase genes in Carboxydothermus hydrogenoformans Z-2901.Ind.J.Biotech.Vol 12,pp 356-363.  

37.N.Radhakrishnan, S. Ashok, V. Kavitha, G. Rameshkumar, A. Gnanamani (2013) Molecular docking studies of L-cysteine (a non-essential sulfur containing amino acid) as a potent Tyrosinase inhibitor.J. Appl. Cosmetol.31, 183-189.                  

36.S.Sangeetha, S. Ranjitha, K. Murugan, G. Ramesh Kumar (2013) Breast cancer specific Histone deacetylase Inhibitors / Lead Discovery using Molecular Docking and Descriptor Study. Trends in Bioinform.6:25-44.

35.N.Radhakrishnan,S.Ashok,V.Kavitha1,G.Ramesh kumar and A.Gnanamani  (2013) Molecular docking  studies of embelin (simple natural benzoquinone) and its derivatives as a potent tyrosinase inhibitor. Journal of Chemical and Pharmaceutical Research, 5(10):320-326.

34.Ashok Selvaraj, Venil Sumantran, Nupoor chowdhary and  Gopal Ramesh Kumar (2013) Prediction and classification of ABC transporters in Geobacter sulfurreducens PCA using computational approaches. Current Bioinformatics Volume 9(2) (2014).                                   

2012

33.PM  Sivakumar, S. Naga Vignesh, G. Ramesh Kumar and Mukesh Doble (2012) Computational approaches to enhance activity of Taxanes as antimitotic agent. Medicinal Chemistry Research.21(9)2557-2570.        

32.Lakshamanan Jagannathan, Kavitha Swaminathan,S. Mathan Kumar,G.Ramesh Kumar and Aparajita Dey (2012) Bio-informatics based analysis of genes implicated in alcohol mediated liver injury.GENE.494(1):130-9.                                              Rajadurai Chinnasamy Perumal,

31.Ashok Selvaraj, Saranya Ravichandran, Gopal Ramesh Kumar (2012) Computational Kinetic Studies of Pyruvate Metabolism in Carboxydothermus hydrogenoformans Z-2901 for improved Hydrogen Production. Biotechnology and Bioprocess Engineering.17:565-575.          

30.Periyasamy Sivamani, Ganesan Singaravelu, Venkatesan Thiagarajan, Tamilarasu Jayalakshmi and Gopal Ramesh Kumar (2012) Comparative molecular docking analysis of essential oil constituents as elastase inhibitors. Bioinformation 8(10):457-460.    Ponnurengam Malliappan

29.Sivakumar, Naga Vignesh Selvaraj, G. Ramesh, J. Mohanapriya, Veluchamy Prabhawathi and Mukesh Doble (2012) Computational Approaches To Improve Aggrecanase-1 Inhibitory Activity Of (4-Keto) Phenoxy) Methyl  biphenyl-4-Sulfonamide: Group Based QSAR and Docking Studies. Medicinal  Chemistry,Vol 8, No 4,2012, 673-682.                 Priyadarshan

28.Kathirvel, Gopal Ramesh Kumar and Kavitha Sankaranarayanan (2012) A Computational prediction of conserved microRNA targets of ion channels in vertebrates. Current Bioinformatics.Vol 8, No 1,93-111.

27.T.Jayalakshmi, P. Krishnamoorthy, G. Ramesh kumar, P. Sivamani and C. G. Aiswariya lakshmi (2012) Application of pure keratinase on keratinous fibers to identify the keratinolytic activity. Journal of Chemical and Pharmaceutical Research. 4(6):3229-3233.

26.Jayalakshmi T, P. Krishnamoorthy, G. Ramesh kumar, V. Thiagarajan and P. Sivamani (2012) Antifungal activity of geraniol against keratinase producing infectious dermatophytic fungi. Int. J. Curr. Sci.  3: 39-44.

2011

25.T.K.Subazini  and G.Ramesh Kumar (2011) Characterization of Lovastatin biosynthetic cluster proteins in Aspergillus terreus strain ATCC 20542.Bioinformation 6(7): 250-254.                                            

24.G.Sailakshmi,Tapas Mitra, A. Gnanamani,S. Thirupathy Kumara Raja,T. Thiruselvi, Naga Vignesh Selvaraj, Gopal Ramesh and A. B. Mandal (2011) Bonding interactions and stability assessment of biopolymer material prepared using type III collagen of avian intestine and anionic polysaccharides. J Mater Sci: Mater Med. 22(6):1419-29.                                                                                                                               

23.T.Jayalakshmi, P.Krishnamoorthy, G.Ramesh kumar , P.Sivamani (2011) Optimization of culture conditions for Keratinase production in Streptomyces sp. JRS19 for Chick feather wastes degradation. J. Chem. Pharm. Res.,3 (4):498-503.

22.T.Jayalakshmi1, P.Krishnamoorthy, G. Ramesh kumar and P.Sivamani (2011) Docking Conformation of Bacillus licheniformis Keratinase enzyme and PMSF ligand. Drug Invention Today.3 (8), 200-202.

21.T.Jayalakshmi, P. Krishnamoorthy, G. Ramesh Kumar and P. Sivamani (2011) The Microbiological Quality of Fruit Containing Soft Drinks from Chennai. J. Chem. Pharm. Res.,  3(6):626-630.

20.R Narayanaswamy, A Gnanamani, Sangeetha Shanmugasamy, Ramesh Kumar Gopal and Asit Baran Mandal (2011) Bioinformatics in crosslinking chemistry of collagen with selective crosslinkers.BMC Research Notes.4:399.doi:10.1186/1756-0500-4-399.

19.Chinnasamy Perumal Rajadurai,Thankaswamy Kosalai Subazini and Gopal Ramesh Kumar (2011) An integrated re-annotation approach for functional predictions of hypothetical proteins in microbial genomes. Current Bioinformatics.Vol.6 (4):450-461.

18.R. Vijayaraghavan , G. Jayababu , R. Prasad , P.E Thirugnanam, Gayathri Shivkumar , V.T. Sriraam  and G. Ramesh Kumar (2011) Bio-analytical method development and validation for omeprazole using LC-MS / MS.IJPSR,Vol.2(9):748-759.

17.Tapas Mitraa,G. Sailakshmia,A. Gnanamani,S.Thirupathi Kumar Rajaa, T. Thiruselvi,V. Mangala Gowri, Naga Vignesh Selvaraj, Gopal Ramesh, A.B. Mandal (2011) Preparation and characterization of a thermostable and biodegradable biopolymers using natural cross-linker. Int.J.Biol.Macromol.48:276–285.                             

16.T.Jayalakshmi,P. Krishnamoorthy,G.Ramesh Kumar and P.Sivamani (2011) Characterisation and Identification of Feather-Degrading Streptomyces sp for Chick Feather Wastes Degradation. Int. J. Biotech. Bioeng. Res..2(2):169–174.

15.T.Jayalakshmi ,P.Krishnamoorthy ,G.Ramesh kumar  and P.Sivamani (2011) Purification and characterization of  Keratinase enzyme from Streptomyces species JRS 19.New York Science Journal,4(4):59-67.

14.P.Vijayalakshmi, G.Ramesh Kumar, C.P.Rajadurai, P.Daisy (2011) Functional genomics and reverse vaccinology approach to identify better vaccine for tuberculosis. International Journal of BioSciences and Technology (2011)4(4):23-28.  

2010

13.Jayashree Mohandass, Saranya Ravichandran , Koganti Srilakshmi  , Chinnasamy Perumal Rajadurai , Sangeetha Shanmugasamy  and Gopal Ramesh Kumar (2010) BCDB- A Database for Breast Cancer Research and Information. Bioinformation. 5(1) 1-3.         

12.Jayalakshmi,T.Krishnamoorthy,P.Ramesh kumar, G and P.Sivamani (2010) Isolation and Screening of a Feather-Degrading Keratinolytic Actinomycetes from Actinomyces sp. Journal of American Science.6(12):45-48.

11.Kalyaanamoorthy Subha, Gopal Ramesh Kumar, Rajasekaran Rajalakshmi and Ganesan Aravindhan (2010) A Novel Strategy for Mechanism Based Computational Drug Discovery. Biomarkers in Cancer.2:35–42.

10.Vijayaraghavan R and G. Ramesh Kumar (2010) Impact of phase zero trials (MICRO-DOSING) in Clinical Trial Research. Int.Journal of Appl.Biology and Pharma.Technol. (2):486-491.                                     

9. Chinnasamy Perumal Rajadurai and Gopal Ramesh Kumar (2010) Functional and comparative genomics studies on Carboxydothermus hydrogenoformans specific to CO-metabolism and hydrogen production. Online Journal of Bioinformatics.11 (1):90-105. Link

2009

8.Sarmistha M,Pradhan S.K, Ramesh Kumar G (2009) An Insilico Approach To Identify Better 20s Type Proteosomal Inhibitor Through Analysis Of Binding Affinity.Bioinfrontiers.1:12-19.

7. G. Aravindhan, G. Ramesh Kumar, R. Sathish Kumar and K. Subha (2009) AJAX Interface: A Breakthrough in Bioinformatics Web Applications. Proteomics Insights 2 1-7.

6. G. Aravindhan, R. Sathish Kumar, K. Subha, T.K.Subazini, Alpana Dey, Krishna Kant and G. Ramesh Kumar (2009) AIM-BLAST-AJAX Interfaced Multisequence Blast. Proteomics Insights 2 9-13.

5. Gopal Ramesh Kumar, Thankaswamy Kosalai Subazini, Kalyanamoorthy Subha, Chinnasamy Perumal Rajadurai and Latha Prabakar (2009) CanGeneBase (CGB) - a database on cancer related genes. Bioinformation. 3(10),422-424.

4. K Palani Kannan, TK Subazini, CP Rajadurai, S Naga Vignesh and G Ramesh Kumar (2009) Computational motif signature discovery and validation of gene prediction in Aspergillus terreus NIH 2624. International Journal of Computational Intelligence in Bioinformatics. 2(1),13-19.

3. Gopal Ramesh Kumar, Ganesan Aravindhan, Thankaswamy Kosalai Subazini and Radhakrishnan Sathish Kumar (2009) Bioinfotracker: A novel system for advanced genome functional insight. Journal of Biological Sequence. pp. 046-049.

2008

2. Kalyanamoorthy Subha and Gopal Ramesh Kumar (2008) Assessment for the identification of better HDAC inhibitor class through binding energy calculations and descriptor analysis.Bioinformation.3(5), 218-222.

2006

1. Latha P, Kalaiselvi P, Varalakshmi P, Rameshkumar G (2006) Characterization of histone (H1B) oxalate binding protein in experimental urolithiasis and bioinformatics approach to study its oxalate interaction. Biochem Biophys Res Commun.23; 345(1): 345-54.