Nitric Oxide

Angiogenesis

Liver Angiogenesis

Endothelium in Extreme Environment

Hypogravity

 

Discoveries

Thalidomide targets sGC..

Ultralow cadmium inactivates eNOS.....

Ang001 antagonizes angiogenesis.....

Microgravity promotes angiogenesis.

Current Activities

The European Union (EU) and Marie Curie Program [more...]

Nature Publishing Group travel award 2010

Best Poster Award at Cancercon 2010

Best Poster Award at SFRR 2010

Awarded Visiting student fellowship by UWA, Perth - 2009

Selected for Presentation at GORDON Conference-Thiol mediated stress response and signaling- 2008

Selected for Presentation at EURO CONFERENCE ON APOPTOSIS -2008

Awarded BOEHRINGER INGELHEIM FONDS travel fellowship - 2008

Best Investigator Award at SFRR- 2007

Awarded IUBMB WOOD WHELAN Fellowship 2007

Selected for Presentation at GORDON Conference- Nitric Oxide 2007

 

Positions Open

 

 

 

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suvro

Nitric oxide, a gaseous signaling molecule, is implicated in various physiological events from vascular smooth muscle relaxation to blood vessel formation, extending to pathophysiology to patholgy, ranging from stroke to cancer.

 

The core research interest of Vascular Biology Lab is to understand the nitric oxide signaling in endothelium.

 

 

 

 

 

 

 

 

Recent Publications and patents…..

 

  1. Kolluru GK, Siamwala JH, Chatterjee S. eNOS phosphorylation in health and disease. Biochimie. (In Press). [pubmed]
  1. Kolluru GK, Sinha S, Majumder S, Muley A, Siamwala JH, Gupta R, Chatterjee S. Shear stress promotes nitric oxide production in endothelial cells by sub-cellular delocalization of eNOS: A basis for shear stress mediated angiogenesis. Nitric Oxide. 2010;22(4):304-315. [pubmed]
  1. Jamila H Siamwala , Himabindu Reddy.S,  Syamantak Majumder, Gopi Krishna Kolluru, Ajit Muley,  Swaraj Sinha, Chatterjee S (2010). Simulated microgravity perturbs actin polymerization to promote nitric oxide associated migration in human immortalized Eahy926 cells. Protoplasma (In Press). [pubmed]
  1. Ranju Kumari et al., Chatterjee S (2010). Calreticulin Transacylase: Genesis, mechanism of action and biological applications. Biochimie (In Press). [pubmed]
  1. Jetti SK, Swain SM,  Majumder S,  Chatterjee S, Venkateshamurthy P, Bera A (2009) Evaluation of the role of Nitric Oxide in acid sensing ion channel mediated cell death. Nitric Oxide 2010; 22(3):213-9. [pubmed]
  1. Muley A,  Majumder S, Kolluru GK, Parkinson S, Viola H, Hool L, Arfuso F, Ganss R, Dharmarajan A , Chatterjee S (2010) Secreted Frizzled-Related Protein 4: An Angiogenesis Inhibitor. . Am J Pathol. 2010;176(3):1505-16. [pubmed]
  1. Chandrasekaran K, Swaminathan K, Chatterjee S, Dey A (2009) Apoptosis in HepG2 cells exposed to high glucose. Toxicology In Vitro 2010;24(2):387-96. [pubmed]
  1. Barh D, Kumar A, Chatterjee S, and Liloglou T (2009) Molecular Pathogenesis and Drug Targets in Cardiac Myxoma. Curr Cancer Drug Targets. 9(6):705-16. [pubmed]
  1. Majumder S, Rajaram M, Muley A, Himabindu Reddy S, Tamilarasan KP, Kolluru GK, Sinha S, Siamwala JH, Gupta R, Ilavarasan R, Venkataraman S, Sivakumar KC, Anishetty S, Pradeep Kumar G, Chatterjee S. (2009) Thalidomide attenuates nitric oxide driven angiogenesis by interplaying with soluble guanylate cyclase. Br J Pharmacol. 158(7); 1720-1734. [pubmed]
  1. Majumder S, Chatterjee S, Lee JO and Muralidhar K. Antiangiogenic Activity of Buffalo Growth Hormone. Science and Culture, Vol. 76 (Sep-Oct), 2009.  
  1. Majumder S, Gupta R, Himabindu Reddy S., Sinha S, Muley A, Kolluru GK, Chatterjee S. (2009) Cadmium attenuates bradykinin driven nitric oxide production by interplaying with the localization pattern of endothelial nitric oxide synthase. Biochem Cell Biol. 87(4):605-20. [pubmed]
  1. Arora S, Tyagi YK, Kumar A, Majumder S, Saluja D, Raj HG, Chatterjee S, Saso L, Prasad AK, Singh PV (2009) The Role of Calreticulin Transacetylase in the Activation of Human Platelet Nitrite Reductase by Polyphenolic Acetates. Biological and Pharmaceutical Bulletin.  32(2):161-5. [pubmed]
  1. Kolluru GK, Tamilarasan KP, Rajkumar AS, Geetha Priya S, Rajaram M, Saleem NK, Majumder S, Jaffar Ali BM, Illavazagan G, Chatterjee S. (2008) Hypoxia promotes leakiness in endothelium: Nitric oxide-cGMP shields the endothelial cells from hypoxia-mediated leakiness. Eur. J. Cell Biol. 87:147-61. [pubmed]
  1. Majumder S, Muley A, Kolluru GK, Saurabh S, Tamilarasan KP, Chandrasekhar S, Reddy H, Purohit SB, Chatterjee S (2007) Cadmium reduces nitric oxide production by impairing phosphorylation of endothelial nitric oxide synthase: A basis for cadmium-mediated endothelial dysfunction. Biochem Cell Biol 86(1):1-10. [pubmed]
  1. Majumder S, Tamilarasan KP, Kolluru GK, Muley A, Nair C M, Omanakuttan A, Murty KVGK and Chatterjee S. (2007) Activated pericyte attenuates endothelial functions: Nitric oxide cGMP rescues activated pericyte associated andothelial dysfunctions.  Bicohem Cell Biol. 85 (6):709-20. [pubmed]
  1. Tamilarasan KP, Kolluru GP, Rajaram M, Indhumathy M, Saranya R, Chatterjee S (2006). Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells. BMC Cell Biol. 4;7:17. [pubmed]
  1. Kolluru GK, Tamilarasan KP, Geetha Priya S, Durgha NP, Chatterjee S (2006) Cadmium induced endothelial dysfunctions: Consequence of defective migratory pattern of endothelial cells in association with poor nitric oxide availability under cadmium challenge. Cell Biol. Int. 30(5): 427-38. [pubmed]

 

Patent

Awarded an International Patent that claims anti-angiogenesis potential of sFRP4 in 2008.


For further discussions, collaborations and comments contact

Dr.Suvro Chatterjee
Research Scientist
AU-KBC Research Centre
Anna University, INDIA
Ph: +91-44-22234885
Fax: +91-44-2222711
Extn:148

suvro@au-kbc.org