POSITION
CURRENTLY
Member Research Staff (2004-till date)
AU-KBC Research Centre,
MIT, Anna University, Chennai.
Wellcome Trust Post Doctoral Fellow (2003-2004)
AU-KBC Research Centre,
MIT, Anna University, Chennai.
Project Director - (2001- 2003)
Molecular Bioscience Pvt Ltd.,Chennai. India.
Lecturer in Microbiology / Biotechnology SRM, Adhiparasakthi and Asan Memorial Colleges (1999-2001).
Chief Microbiologist (1998) ABL Biotechnologies Ltd.,Chennai.
Chief Chemist (1994-1997) S&S Industries and Enterprises Ltd.,Chennai.
Scientist Fellow (1992-1994) National Environmental Engineering Research Institute, (NEERI) Nagpur.
Consultant / Technologist / Research Fellow / Research Assistant (1985-1991) MCRC, Chennai.
OTHERS
Council of Scientific and Industrial Research (CSIR) Fellowship -JRF-NET, GOVT., OF INDIA.
PhD students-3
MS students –3
PROJECTS
Bioinformatics Approach for identification of hypothetical ORF in Bacterial genome & hydrogen production pathways –DIT sponsored project (2007-2008)
BIOINFORMATICS SKILLS
R&D IN BIOINFORMATICS- Experience in
FUNCTIONAL GENOMICS,
MOLECULAR MODELLING AND DOCKING,
TOOL AND DATA BASE DEVELOPMENT,
GENE EXPRESSION AND MICROARRAY DATA ANALYSIS,
SYSTEMS BIOLOGY,
DRUG DISCOVERY AND VACCINE DEVELOPMENT,
ALGORITHM DEVELOPMENT,
DATA MINING AND KNOWLEDGE DISCOVERY,
AUGMENTATION OF FERMENTATION PRODUCTS,
MISSING ENZYMES PREDICTION FOR TAXOL PATHWAY,
INDUSTRIAL EXPERIENCE
For the following microorganisms (17), complete functional annotation has been carried out using different bioinformatics tools and databases with data curation. (Lion Bioscience, Germany has given the project). Halobacterium sp. NRC-1
Escherichia coli K-12
Pseudomonas aeruginosaPA01
Neisseria menigitidisMC58
Aquifex aeolicus
Methanococcus jannaschii
Helicobacter pylori 26695
Archaeoglobus fulgidus
Haemophilus influenzae
ycobacterium tuberculosis
Chlamydia muridarum
Lactobacillus lactis
Pyrococcus abyssi
Chlamydia trachomatis
Mycoplasma pneumoniae
Escherichia coli 0157
Pasteurella
Total 40,735 ORFS
COMMENT ON THE WORK:
'Molecular Bioscience Pvt Ltd (MBS) collaborated with us for performing data analysis services for a project in functional genomics. The project was completed 3 weeks ahead of time by MBS. We have found the quality of services of MBS to be excellent and on par with the work done in-house. We have no hesitation in commending the services of MBS to any prospective collaborator.'
Lion Bioscience AG, the best- known name in the world in Life Science Informatics.
‘It's clear you’re doing an excellent job and providing a valuable service to your clients’ –
Nathan (Nat) Goodman, who helped found Whitehead/MIT Center for Genome Research and currently Senior Research Scientist, The Institute for Systems Biology, Seattle, Washington.
BIOINFORMATICS TOOLS Usage-Experience in more than 100 tools (Both academic and Commercial) ranging from Genomics to Systems Biology (genomeScout and bioScout, Lion Bioscience; GCG package; EMBOSS; Modeller and AutoDock ; E-Cell)
COMPUTER SKILLS
*Programming languages: VB, C, C++ and Java
*Scripting Language: Perl and Python
*OS: WINDOW'S XP, WINDOW'S NT AND LINUX (FEDORA)
*DATABASE: SQL and ORACLE 9i
*Documentation tools: MS OFFICE 2000 (Word, Excel, Power point and Access)
*Certificate course in "Computers in Office Management" at Committee on Science and Technology for Developing Countries (COSTED) India (1989). Learned MS DOS, Basic, WS, dbase III plus and Lotus 1-2-3.
PUBLICATIONS:
Ramesh Kumar, G and T.M.Vatsala (1989) Hydrogen production from glucose by Citrobacter freundi, Ind. J. Exp. Biol. 27:824-825.
Vatsala,T.M and G.Ramesh Kumar (1988) Biohydrogen production from industrial wastes using locally isolated Citrobacter freundii . Proceedings of the 8th Miami International Conference on Alternative Energy Sources (8–MICAES), 14-16 December 1087,Miami beach Florida,USA pp 630-632.
Badrinath,S.D.,Ramesh Kumar,G. and C.V.Chalapathi Rao (1994) Metabolic engineering and metabolite addition for augmentation of manganese bioleaching from its ore. National Symposium on Bioproducts Processing at Malaysia, 4-7, January 1994.
Latha P, Kalaiselvi P, Varalakshmi P, Rameshkumar G (2006) Characterization of histone (H1B) oxalate binding protein in experimental urolithiasis and bioinfor-
matics approach to study its oxalate interaction.Biochem Biophys Res Commun.23; 345(1): 345-54.
PAPER AND POSTER PRESENTATION/ INVITED LECTURES/ WORKSHOPS / TRAINING / SEMINAR / CONFERENCE ATTENDED
2001
1. Presented the following posters at International Symposium on "Progress in Drug Discovery and Development Sciences", Jan 17-19, 2001, AstraZeneca, Bangalore, India
a.Comparative genomics for drug discovery and development using Mycoplasma genitalium and M.pneumoniae.
b.Metabolic Pathway Discovery (MPD) for drug discovery and development using taxol as a model.
2004
1.Presented the following poster at International Symposium on " Drug Discovery to Manufacturing: Global Partnering & New Science ’October 18-20, 2004, Mumbai, India.
Augmentation of lovastatin production and process improvement through bioinformatics and systems biology approach
2. Workshop on Open Access at MS Swaminathan Research Foundation (6-8 May 2004).
3. Inauguration of Bioinformatic Resources and Applications Facility and Discussion Meet, June 14th, 2004 C-DAC, Bangalore.
4.Seminar cum Workshop on Structural Bioinformatics, IISc, Bangalore , August 11th to 13th, 2004).
Invited Lectures
1.Invited lecture: Bioinformatics tools in Proteomics, Metabolomics and Systems Biology. Organized by DIPAS, DRDO, New Delhi (4th November, 2004).
2.Invited lecture:Pharmacogenomics –An Introduction,St Josephs College of Engineering,Chennai.
3.Invited Lecture:Pharmacogenomics and Drug Discovery, SRM Deeemed University,Chennai.
4.Invited lecture: Pharmacogenomics –Recent trends ,VIT,Vellore.
5.Invited lecture: Bioinformatics –An Introduction, Sankar Nethralaya,
Chennai (24.11.2006).
2005
EDUCATION AND BEYOND
2006
1.Attended a training programme on Advanced Microarray Technology at IISc, Bangalore (30 January 2006)
POPULAR LECTURES PRESENTED IN BIOINFORMATICS
1.Dr MGR Educational and Research Institute (2002)
2.Madras University (2003)
3.Inbios (Bioinformatics Association)(2003)
4.Bharath Institute of Higher Education and Research (2004)
5.DKM College for Women (2005)
6.Pentasoft Technologies (2005)
BIOINFORMATICS TEACHING AND TRAINING
Course content development, Teaching and Project guidance
Training Programmes conducted at Molecular Bioscience Pvt., Ltd.,Chennai
2002-2003
Post Graduate Diploma in Bioinformatics (3 Months)
Training Programmes conducted at AU KBC, MIT, Anna University:
2004
1.Short Course in Bioinformatics Tools for Life Sciences (Feb 25-27,2004)
2.Certificate Programme in Bioinformatics (May 25-29,2004)
3.Certificate Programme in Bioinformatics (June 22-26,2004)
4.Drug Discovery and Development through Bioinformatics (September 21-25, 2004)
5.Certificate Programme in Bioinformatics (October 5-9, 2004)
2005
1.Certificate Course in Bioinformatics Tools for Life Sciences (Feb 22-25,
2005)
2. Certificate Course in Bioinformatics (June 21-25,2005)
3. Drug Discoveries and Development through Bioinformatics (July 19-23,2005)
4. Bioinformatics approach for Drug Discovery and Development (27.12.2005-31.12.2005)
2006
1. Certificate Course in Bioinformatics (7.2.2006-11.2.2006)
2. Short term course in Microarray Data Analysis (29.6.2006-30.6.2006)
3.Certificate Course in Drug Discovery and Development through Bioinformatics (11.7.2006-15.7.2006)
4.Certificate Course in Bioinformatics (8.8.2006-12.8.2006)
2007
1. Certificate Course in Bioinformatics (22.5.2007-26.5.2007)
2. Certificate Course in Drug Discovery and Development through Bioinformatics
(19.6.2007-23.6.2007)
3. Certificate Programme in Clinical Research (4.9.2007-8.9.2007)
4. Certificate Programme in Drug Discovery and Development through Bioinformatics (9.10.2007-13.10.2007)
SATELLITE EDUCATION
Conducted Certificate level training programe in Bioinformatics,
Everonn,Chennai -2005 and 2006
VISITING FACULTY
Bioinformatics (Elective) Course offered to B.E., Electronics and Communications Engineering (Final Year) (2005)
EIA PROJECTS
Projects involved at NEERI, Nagpur
Environmental Impact Assessment for Aerated Lagoons Construction, MCGB, Bombay, 1990
Environmental Impact Assessment for Sandur Manganese and Iron Ore Ltd. (SMIORE), Sandur, 1991
Environmental Impact Assessment for BALCO, 1991
Environmental Impact Assessment for Jayamkondam Lignite Power Project, 1991
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DATABASES